模型信息
中文名称:SARS-CoV-2 RNA BetaCoV/Munich/BavPat1/2020 滴鼻感染雪貂模型
英文名称:SARS-CoV-2 RNA BetaCoV/Munich/BavPat1/2020 nose drop infected ferret model
类型:SARS-CoV-2感染动物模型
分级:NA
用途:用于新冠肺炎COVID-19致病机制研究、疫苗和药物评估。
研制单位:鹿特丹伊拉斯姆斯大学@@https://www.erasmusmc.nl/en/research/departments/viroscience
保存单位:鹿特丹伊拉斯姆斯大学@@https://www.erasmusmc.nl/en/research/departments/viroscience
研究背景
暂无介绍
制备方法
ferrets were inoculated intranasally with a strain of SARS-CoV-2 isolated from a German traveller returning from China. Four donor ferrets were inoculated intranasally with 6*10**5 TCID50/ml of SARS-CoV-2 virus diluted in 500μl of phosphate-buffered saline (PBS) (250 μl instilled dropwise in each nostril). The air flow rate from the donor to the recipient ferret was ~100 L min**−1and the temperature of the room was between 21 and 22 °C.
评价验证
暂无介绍
生物安全性
暂无介绍
讨论与结论
暂无介绍
了解中析
实验室仪器
合作客户
